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Teaching Video NeuroImages: Jaw Clonus in Amyotrophic Lateral Sclerosis
We present a case of amyotrophic lateral sclerosis (ALS) in a middle-aged woman who presented with a 2-year history of dysarthria and dysphagia. On examination,…
Sensitivity of brain MRI and neurological examination for detection of upper motor neurone degeneration in amyotrophic lateral sclerosis
Objectives To investigate sensitivity of brain MRI and neurological examination for detection of upper motor neuron (UMN) degeneration in patients with amyotrophic lateral sclerosis (ALS).…
Pearls & Oy-sters: Gait Instability, Jaw Dystonia, and Horizontal Diplopia in a Woman With Anti-Ri Antibodies and Breast Cancer
A 40-year-old woman was admitted for 6 months of progressive gait disturbance, lower limb–predominant weakness, stiffness, falls, jaw dystonia, horizontal diplopia, and weight loss. Neurologic…
Anti-IgLON5 Disease: A New Bulbar-Onset Motor Neuron Mimic Syndrome
Objective To expand the spectrum of anti-IgLON5 disease by adding 5 novel anti-IgLON5–seropositive cases with bulbar motor neuron disease-like phenotype. Methods We characterized the clinical…
Nonmotor Symptoms in Amyotrophic Lateral Sclerosis and Their Correlation With Disease Progression
Objectives: Motor neuron disease is a progressive neurodegenerative disease involving upper and lower motor neurons. Nonmotor symptoms (NMS) are part of disease manifestation. We aim to report the…
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