Objective Progranulin-related frontotemporal dementia (FTD-GRN) is a fast progressive disease. Modelling the cascade of multimodal biomarker changes aids in understanding the aetiology of this disease…
Introduction Clinical trials in amyotrophic lateral sclerosis (ALS) aim to identify treatments that can slow functional decline or prolong survival time. In the absence of…
Objective We aimed to investigate the validity of urinary N-terminal titin fragment as a biomarker for amyotrophic lateral sclerosis (ALS). Methods We consecutively enrolled patients…
CASE DESCRIPTION A 45-year-old Jordanian man had 2 weeks of gradual onset headache, neck stiffness and loss of vision. The headache was occipital with pulsatile tinnitus…
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