Author Response: Association of Guideline Publication and Delays to Treatment in Pediatric Status Epilepticus

We thank Drs. Albuja, Bensalem-Owen, and Villamar for their comment on our study1 and for their crucial contribution, highlighting the developments toward improving status epilepticus treatment in this pilot study in 19 adult patients during inpatient care at a single center2 and our publication. We are entirely aligned with these essential suggestions and applaud the authors for their crucial contribution. Similarly—and simultaneously to the authors’ accomplishment—pediatric investigators were able to improve inpatient treatment times in children at a single center.3 Most ongoing delays continue to occur in patients with intermittent refractory status epilepticus—related to difficulties in assessment whether convulsive status epilepticus persists—and in the outpatient setting.4 Our group is actively working on measures that can identify ongoing seizures—not only at a single center but also for larger populations in multicenter settings and in the outpatient setting.5 We agree that—among other approaches such as implementing novel technologies and quality improvement techniques—learning from previous stroke treatment efforts will play an important role.6 We are grateful for the chance to add this outlook to our current article and congratulate Drs. Albuja, Bensalem-Owen, and Villamar on this innovative milestone toward our shared goal of implementing improved status epilepticus care for our patients.

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