Teaching NeuroImages: Cytotoxic Lesion of the Corpus Callosum Secondary to Influenza A

A 42-year-old man presented with respiratory symptoms, followed by ptosis, ageusia, dysarthria, and left hand weakness. MRI showed a lesion within the splenium of the corpus callosum (figure). Vascular and toxic-metabolic workup was unremarkable. Nasopharyngeal swab revealed Influenza A positivity. Symptoms fully resolved after oseltamivir treatment.

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