Mind over motor

Quality of life in dystonia largerly depends on the occurrence and severity of non-motor symptoms

In the paper by Junker et al, the contributors to quality of life (QoL) were investigated in a large sample of 603 subjects with isolated idiopathic dystonia.1 Dystonia is classically seen as a motor disorder and this mirrors the characteristics of available disease severity scales and treatment options. However, research over the last decade has shown that treatment strategies merely focused on the management of motor manifestations do not guarantee an improvement of QoL, the real target of our interventions.

Various non-motor symptoms (NMS) are highly prevalent in dystonia and sometimes even define its diagnostic definitions, such as in Myoclonus-Dystonia.2 Many studies have already investigated the role of NMS in QoL of patients with dystonia, although the mechanisms of the association are still unclear and most likely multifactorial.3 Studies to…

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