Author Response: Characterizing Opioid Use in a US Population With Migraine: Results From the CaMEO Study

We thank Dr. Gupta for his comments on our article.1 We agree that patterns of opioid use vary by region of the world and acknowledge that opioid treatment of migraine may be particularly problematic in the United States.2 We also agree that metoclopramide given intravenously is an important option in the emergency department, where opioids are often used.2–4 There are also a number of other acute treatment options—including neuromodulation—and oral treatments, such as nonsteroidal anti-inflammatory drugs, triptans, gepants, and ditans.5

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