Radiation-Induced Bilateral Oculomotor Nerve Palsy 20 Years After Radiation Treatment

Radiation therapy, a common treatment for head, neck, and brain cancers, can result in iatrogenic damage to neural tissue, including cranial nerves.1-4 Postradiation neurologic injuries present during acute (days to weeks after radiation), early-delayed (weeks to months), or late-delayed (beyond 6 months) phases.5 Cranial neuropathy is uncommon and occurs during the late-delayed phase, usually months to a few years after radiation treatment,1,3-5 but can also occur decades later.6 Here, we describe a presentation of bilateral, sequential, radiation-induced oculomotor nerve palsy that developed after 2 decades.

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