Author Response: Phenotypic Variability in ALS-FTD and Effect on Survival

myneuronews June 8, 2021

0 Comments

We thank Dr. Abe for his interest in our study¹ that investigated survival in patients with amyotrophic lateral sclerosis-frontotemporal dementia (ALS-FTD). Specific comparison of motor and cognitive presentations in ALS-FTD established that patients with a motor onset of their disease had reduced survival—which was associated with increased motor cortex atrophy—suggesting that survival may be mediated by motor function and other critical physiologic aspects.

Read article at journal's website

Categories: General Neurology

Editors' Note: Phenotypic Variability in ALS-FTD and Effect on Survival

Dr. Ahmed et al. examined initial presentations and cognitive and behavioral profiles in 59 patients with amyotrophic lateral sclerosis and frontotemporal dementia (ALS-FTD) and 39…

myneuronews June 8, 2021

0 Comments

Amyotrophic Lateral Sclerosis-Frontotemporal Dementia: Shared and Divergent Neural Correlates Across the Clinical Spectrum

Background and Objectives A significant overlap between amyotrophic lateral sclerosis (ALS) and behavioral variant of frontotemporal dementia (bvFTD) has been observed at clinical, genetic, and…

myneuronews January 25, 2022

0 Comments

Reader Response: Phenotypic Variability in ALS-FTD and Effect on Survival

I read the article by Ahmed et al.1 and generally agree with their comments. However, I offer some insights. First, Yuasa2 reported a case of…

myneuronews June 8, 2021

0 Comments

Neural Variability in the Prefrontal Cortex as a Reflection of Neural Flexibility and Stability in Patients With Parkinson Disease

Background and Objectives Functional near-infrared spectroscopy (fNIRS) studies provide direct evidence of the important role of the prefrontal cortex (PFC) during walking in aging and…

myneuronews February 22, 2022

0 Comments

Characterizing the Clinical Features and Atrophy Patterns of MAPT-Related Frontotemporal Dementia With Disease Progression Modeling

Background and Objective Mutations in the MAPT gene cause frontotemporal dementia (FTD). Most previous studies investigating the neuroanatomical signature of MAPT mutations have grouped all…

myneuronews August 31, 2021

0 Comments

Related Articles

Responses