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Clinical Utility of Striational Antibodies in Paraneoplastic and Myasthenia Gravis Paraneoplastic Panels
Objective To critically assess the clinical utility of striational antibodies (StrAbs) within paraneoplastic and myasthenia gravis (MG) serologic evaluations. Methods All Mayo Clinic patients tested…
Favorable Response in Statin-Naive Paraneoplastic Anti-HMGCR Antibody–Associated Myopathy to Single Dose of Rituximab and Persistent Remission With Management of Underlying Lung Cancer
Anti-HMGCR myopathy is a subtype of immune-mediated necrotizing myopathy, typically associated with exposure to statins, although a sizable minority in some cohorts are statin-naive. Although…
Case of Anti–Single Recognition Particle–Mediated Necrotizing Myopathy After Influenza Vaccination
Immune-mediated necrotizing myopathy is a very rare inflammatory disease affecting skeletal muscles. Immune-mediated necrotizing myopathy may be associated with myositis-specific autoantibodies including anti–single recognition particle…
Steroid-Responsive Myopathy: Immune-Mediated Necrotizing Myopathy or Polymyositis Without Inflammation?
Objective: To describe the clinical course and steroid responsiveness of a patient with subacute proximal symmetric weakness, very high serum creatine kinase activity, and myopathic…
LGI1 encephalitis with squamous lung-cell carcinoma: Resolution after tumor resection
Encephalitis with leucine-rich glioma-inactivated-1 (LGI1) immunoglobulin G (IgG) antibodies classically presents with cognitive impairment and characteristic faciobrachial dystonic seizures.1 In a murine model, human LGI1…
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