Readmissions After Guillain–Barre Syndrome: Nationally Representative Data

imageObjectives:

We aimed to obtain nationally representative data on hospital readmission rates after Guillain–Barre syndrome (GBS).

Methods:

International Classification of Disease, Ninth Revision codes from the 2013 National Readmissions Database identified adult GBS admissions, comorbidities, and readmission diagnoses. Logistic regression estimated odds ratios (ORs) for readmission.

Results:

Of 2109 GBS admissions identified, 20.8% were readmitted within 1 year and 12.2% within 30 days. Age did not predict readmission. Plasmapheresis use showed a nonsignificant trend toward readmission versus intravenous immunoglobulin use [OR 1.43, 95% confidence interval (CI) 1.00–2.051, P = 0.050]. Respiratory failure (OR 1.70, 95% CI 1.23–2.35, P = 0.0014), heart failure (OR 2.14, 95% CI 1.25–3.66, P = 0.0057), and renal failure (OR 2.00, 95% CI 1.20–3.32, P = 0.0078) predicted readmission. Top readmission diagnoses included GBS or chronic inflammatory demyelinating polyneuropathy (42.0%) and sepsis (3.5%).

Conclusions:

One-fifth of GBS patients were readmitted within 1 year. Comorbid illnesses and respiratory complications increased a readmission risk but age did not.

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