Author Response: Dietary Antioxidants and the Risk of Parkinson Disease: The Swedish National March Cohort

We are grateful for Dr. Kawada’s interest in our paper.1 There are indeed discrepancies between findings on vitamin C, beta-carotene, and the risk of Parkinson disease, while the evidence for vitamin E is consistent when considering findings by Yang et al.2 and those in our study.1 Furthermore, 2 meta-analyses reported that a higher intake of vitamin E was found to protect against Parkinson disease,3 whereas no such association was seen with vitamin C3 or beta-carotene.3,4 A recent publication from the Nurses’ Health Study and the Health Professionals Follow-up Study reported an inverse association between dietary vitamin C and Parkinson disease, although the results were nonsignificant after excluding cases occurring during the first 4 years of follow-up. No association was seen between vitamin E and beta-carotene.5

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