Guess Who: dopamine agonist and creativity?

     Creativity is the ability to illustrate what is outside the box from within the box. Oscar Wilde.

To explore whether creativity in people with Parkinson’s disease might be enhanced by dopamine replacement therapy and especially by dopamine agonists, we asked six people with Parkinson’s disease (mean age 70±5 years, evolution over 5.5±2.0 years) visiting our clinic to draw on a blank sheet of paper (for 2 min) the first thing that came to mind. None had current or previous artistic jobs or hobbies. All were independent for activities of daily living, and none had significant cognitive impairment. Five took levodopa alone, and one took dopamine agonist monotherapy. None had evidence of an impulse control disorder using the Questionnaire for Impulsive–Compulsive Disorders in Parkinson’s Disease Rating Scale.

Which patient is taking the dopamine agonist?

Patient 5 is the one taking a dopamine agonist. He is a 65-year-old man with a 3-year disease duration of…

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