Cerebral Venous Sinus Thrombosis With Severe Thrombocytopenia: A Fatal Adverse Event After Johnson & Johnson COVID-19 Vaccination

A high index of suspicion is required to identify the very rare case of CVST after vaccination with an adenovirus vector SARS-CoV-2 vaccine. Headache is very common after vaccination. Onset is within 24 hours. However, headache related to CVST starts 5–7 days after vaccination. This distinction can help clinicians risk stratify headache after SARS-CoV-2 vaccine administration.

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