GAD65 Antibody-Associated Neurologic Disease Presenting With Hemiparkinsonism at Onset

In the correct context, GAD65 antibody-associated neurologic disease should be included in the differential diagnosis for parkinsonism, even hemiparkinsonism, especially in the setting of an acute-to-subacute presentation and the emergence of more prototypic features such as appendicular and truncal muscle stiffness and cerebellar ataxia. Prompt recognition of the condition is critical because early immunotherapy may confer a better prognosis.

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