Reader Response: Automated Quantitative Pupillometry in the Critically Ill: A Systematic Review of the Literature

Opic et al. are to be commended for listing the various factors that can affect the pupillary light reflex (PLR).1 The PLR is like any other medical test because it requires interpretation by a physician who considers the result in the light of other information about the patient to determine a diagnosis and treatment. If the PLR has any value at all, then it seems preferable to get an objective measurement that can be time-stamped and trended over time.

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