Valproate-Induced Reversible Hemichoreoathetosis in a Patient With Rasmussen Encephalitis

A 24-year-old woman with Rasmussen encephalitis diagnosed at age 6 years underwent investigation of involuntary movements. She developed continuous left-sided hemichoreoathetosis at age 11 after addition of valproic acid (VPA) to carbamazepine and phenobarbital therapy. Admission workup was unremarkable, except for toxic VPA levels (129 mg/L). Cessation of movements was observed the day after VPA was discontinued (Video 1).

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