December 7, 2022

When evaluating vaccine efficacy, the conventional measures include a reduction of risk of hospitalization and death. The number of patients dying with or without vaccination is often in the public spotlight. However, when evaluating public health interventions or the burden of disease, it is more illustrative to use mortality metrics that also take into account the prematurity of the deaths, such as years of life lost (YLL) or years of life saved (YLS) due to the vaccination.

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