September 25, 2023

Persistent Post-Concussion Syndrome (PPCS) is a condition that often emerges following mild traumatic brain injuries, including concussions. This syndrome encompasses an array of symptoms such as headaches, dizziness, fatigue, cognitive impairments, and mood changes, which can linger for months or even years post-injury.

Despite extensive research, the mechanisms behind PPCS have remained largely elusive, making it difficult to predict which patients might develop PPCS following a mild traumatic brain injury. Additionally, there is no one-size-fits-all treatment for this condition.

This is why our latest publication, “Functional Overlay Model of Persistent Post-Concussion Syndrome,” is particularly groundbreaking.

In this paper, we present a novel Functional Overlay Model that aims to demystify PPCS by focusing on the interaction between functional and structural factors contributing to the development and perpetuation of symptoms.

The model suggests that an initial brain injury can trigger a cascade of physiological and psychological processes that disrupt the normal functioning of the brain. This disruption may be further aggravated by pre-existing factors, such as genetic makeup, previous injuries, and psychological distress, which can heighten susceptibility to PPCS.

What sets our model apart is its practical applications. By understanding the complex interplay of factors contributing to PPCS, it’s possible to formulate targeted interventions. The Functional Overlay Model proposes that strategies like cognitive behavioral therapy, neurofeedback, and physical exercise can be employed more effectively in treating PPCS.

We believe this new framework not only enriches our understanding but also paves the way for more effective and tailored treatment approaches, ultimately improving the quality of life for patients afflicted with this condition.

Stay tuned for more updates, and don’t hesitate to reach out if you would like more information about this research!

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