Khalid Hamandi, Sandor Beniczky, Beate Diehl, Rosalind H. Kandler, Ronit M. Pressler, Arjune Sen, Juliet Solomon, Matthew C. Walker, Manny Bagary, with ILAE British Chapter Workshop Attendees

Khalid Hamandi, Sandor Beniczky, Beate Diehl, Rosalind H. Kandler, Ronit M. Pressler, Arjune Sen, Juliet Solomon, Matthew C. Walker, Manny Bagary, with ILAE British Chapter Workshop Attendees September 3, 2017

Long term inpatient video-EEG monitoring (VEM) is an essential investigation in tertiary epilepsy centres [1,2]. VEM involves the recording of continuous and simultaneous video, EEG and ECG with a view to capturing clinical events of interest. The recording is typically carried out over 2–5 days, but can be longer according to the clinical situation.… Read More...

Peter Yan, Tamar Melman, Sherry Yan, Munkhzul Otgonsuren, Zachary Grinspan September 3, 2017

Non-convulsive seizures (NCS) affect 8–50% [1–6] of critically ill patients and are associated with non-convulsive status epilepticus (NCSE), which has a high mortality rate of 17–51% [7–9]. Continuous EEG (cEEG) is a valuable tool in diagnosing NCS; however, it is labor and time intensive to review.… Read More...

Maria Stella Vari, Monica Traverso, Tommaso Bellini, Francesca Madia, Francesca Pinto, Carlo Minetti, Pasquale Striano, Federico Zara September 3, 2017

Temporal lobe epilepsy (TLE) is the most common form of focal epilepsy and may be associated with acquired central nervous system lesions or could be genetic.Various susceptibility genes and environmental factors are believed to be involved in the aetiology of TLE, which is considered to be a heterogeneous, polygenic, and complex disorder.… Read More...

Gregg H. Rawlings, Ian Brown, Brendan Stone, Markus Reuber September 3, 2017

Psychogenic nonepileptic seizures (PNES) are one of the most important differential diagnoses of epilepsy. PNES superficially resemble epileptic seizures, but are not associated with epileptiform activity. Instead, PNES are considered to have a psychological basis and can be best understood as a dissociative response to distressing stimuli [1,2].… Read More...

Raphael Johannes Morscher, Christian Rauscher, Wolfgang Sperl, Olaf Rittinger September 3, 2017

Up to 70% of epilepsies have been reported to be related to genetic factors with a continuously enlarging fraction known to be caused by monogenetic alterations [3]. Even with the advent of massive parallel sequencing, the recognition of classical epilepsy-syndromes can be key to rapid diagnosis, which can guide therapy and provide valuable information on prognosis.… Read More...

Vimlesh Soni, Pratibha Singhi, Arushi Gahlot Saini, Prabhjot Malhi, Radha K. Ratho, Baijayantimala Mishra, Sunit C. Singhi September 3, 2017

An acute symptomatic seizure is defined as a clinical seizure occurring in close temporal relationship with an acute central nervous system (CNS) insult, which may be metabolic, toxic, structural, infectious, or inflammatory [1]. Overall acute symptomatic seizures represent nearly 40% of total seizures [2], 40% of all cases of afebrile seizures [3] and 50–70% of status epilepticus episodes [4].… Read More...

Maxine Dibué-Adjei, Igor Fischer, Hans-Jakob Steiger, Marcel Alexander Kamp September 3, 2017

Severe myoclonic epilepsy of infancy (SMEI) was first decribed by Charlotte Dravet in 1978 and later renamed to “Dravet Syndrome” to include atypical and borderline forms as well as to describe the syndrome that persists beyond infancy [11,12]. Dravet syndrome (DS) is an infantile-onset epileptic encephalopathy of childhood involving intractable seizures, recurrent status epilepticus and cognitive decline [13,14].… Read More...

Peter L. Fisher, Adam J. Noble September 3, 2017

Anxiety and depression are highly prevalent in people with epilepsy (PWE); approximately one third of PWE meet diagnostic criteria for an anxiety and/or a depressive disorder during their lifetime [1]. Anxiety disorders are at least as prevalent as depressive disorders, and frequently co-occur with substantial adverse economic, societal and personal consequences [2–4].… Read More...

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