Reymundo Dominguez, Madison Zitting, Qinghai Liu, Arati Patel, Robin Babadjouni, Drew M. Hodis, Robert H. Chow, William J. Mack

Reymundo Dominguez, Madison Zitting, Qinghai Liu, Arati Patel, Robin Babadjouni, Drew M. Hodis, Robert H. Chow, William J. Mack March 27, 2018

Estradiol is a sex steroid hormone known to protect the brain against damage related to transient and global cerebral ischemia. In the present study, we leverage an experimental murine model of bilateral carotid artery stenosis (BCAS) to examine the putative effects of estradiol therapy on chronic cerebral hypoperfusion.… Read More...

Emilija Cvetkovska, Igor Kuzmanovski, Marija Babunovska, Bojan Boshkovski, Tatjana Cepreganova Cangovska, Gordana Kiteva Trencevska March 27, 2018

The traditional perception of mesial temporal lobe epilepsy (MTLE) as a predominantly acquired disorder is challenged due to emerging evidence of familial aggregation. In this study, we ascertained the extent of familial occurrence of epilepsy in MTLE patients, as well as phenotypic heterogeneity in affected relatives.… Read More...

Jing Zeng, Hóngyi Zhào, Zhixin Liu, Weiwei Zhang, Yonghua Huang March 27, 2018

Cerebral microhemorrhage (CMH) is a neuropathological term that could be easily found in cerebral amyloid angiopathy, intracerebral hemorrhages, etc. CMHs could be detected clearly in vivo by magnetic resonance imaging (MRI)–susceptibility-weighted imaging or MRI T2* scan. This terminology is now accepted in the area of neuroimaging.… Read More...

Anna Balcerzyk, Paweł Niemiec, Tomasz Iwanicki, Tomasz Nowak, Ilona Kopyta, Ewa Emich-Widera, Ewa Pilarska, Karolina Pienczk-Ręcławowicz, Marek Kaciński, Janusz Wendorff, Sylwia Górczyńska-Kosiorz, Władyslaw Grzeszczak, Iwona Żak March 27, 2018

Pediatric ischemic stroke is an important cause of morbidity and mortality. As previous studies of children after stroke showed, dyslipidemias were very common in Polish and other European populations. Thus, looking for genetic factors predisposing to pediatric stroke, its symptoms, and outcome, we have analyzed 2 polymorphisms of the upstream stimulating factor 1 (USF-1) gene.… Read More...

Lu Wang, Chenchen Wei, Linghui Deng, Ziqiong Wang, Mengyuan Song, Yao Xiong, Ming Liu March 27, 2018

Hemorrhagic transformation is a serious complication of acute ischemic stroke, which may cause detrimental outcomes and the delayed use of anticoagulation therapy. Early predicting and identifying the patients at high risk of hemorrhagic transformation before clinical deterioration occurrence become a research priority.… Read More...

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