Associations between NMR, electrophysiological, strength and function variables in SMA type 2 and 3

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NatHis-SMA is a prospective multicentre natural history study on spinal muscular atrophy (SMA) type 2 and 3 incorporating a combination of various measurements over 2 years. Among the 81 patients included, 43 patients were aged between 6 and 30 years. Twenty-four patients were SMA Type 2, 9 non-ambulant SMA Type 3 and 10 ambulant SMA Type 3. We present here the analyses on the relationships between skeletal muscle NMR imaging, electrophysiological, strength and function variables on this population of patients.

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