Is grip strength compared to lower extremity measurements sufficient for capturing changes in muscle strength in chronic inflammatory demyelinating polyneuropathy?


Chronic inflammatory demyelinating polyneuropathy (CIDP) is a sensomotoric disorder with proximal and distal muscle weakness in upper and lower extremities. Grip strength measures muscle strength in the distal upper extremities and is a commonly used outcome measure in patients with CIDP. However, several patients with CIDP present with predominant lower extremity weakness. So far, no studies have investigated the relationship between grip strength and outcome measures of lower extremity muscle strength and function.


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