Deciphering neurodegeneration: A paradigm shift from focality to connectivity


“Wet or dry” is the fundamental dichotomy of biomarker research, referring to biofluid vs imaging-based approaches. Biomarker development in neurodegeneration has gained unprecedented momentum in recent years. Despite the substantial diagnostic advantages of molecular PET and biofluid markers, accurate prognostic indicators and sensitive monitoring markers are urgently required both for clinical trial designs and individualized patient care.


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