Anti epileptic drug trials for patients with drug resistant idiopathic generalised epilepsy: A meta-analysis

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Epilepsy is one of the most common neurological conditions affecting 70 million people worldwide [1], with an incidence of 36,000 in Ireland [2]. More than half of patients will achieve seizure control. Approximately 30% of patients will remain drug resistant [3]. Drug resistant epilepsy is defined by the International League Against Epilepsy (ILAE) as a failure of adequate trials of two tolerated, appropriately chosen anticonvulsant drugs, whether as monotherapy or in combination, to achieve sustained seizure freedom [4].

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