Annals of Neurology: Volume 82, Number 5, November 2017

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ON THE COVER: A 3-dimensional z-stack of images taken with a confocal microscope of synapses (stained green for synaptophysin) being phagocytosed by microglia (stained red for CD68), in the spinal cord of a mouse with knockout of the Abcd1 gene. Mutations in this gene in humans cause adrenoleukodystrophy, one component of which is adrenomyeloneuropathy, in which there is loss of spinal cord synapses.

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