Muskelin Coordinates PrPC Lysosome versus Exosome Targeting and Impacts Prion Disease Progression

0

Heisler et al. demonstrate that prion protein intracellular transport is important for the progression of prion disease. They identify a regulatory mechanism of bidirectional prion protein vesicle trafficking and propose a novel transport pathway that connects intracellular lysosomal degradation with extracellular exosome trafficking under neurodegenerative conditions.

Read More...

Leave A Reply