DMD TREATMENT: ANIMAL MODELS

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Optimizing preclinical tools and methods to evaluate therapeutic candidates is critical to improve decision-making about advancing therapies to clinical testing. In collaboration with leading experts in the neuromuscular community and TREAT-NMD network, Charley’s Fund, a patient-founded research nonprofit, organized an effort to address a timely topic of this nature: how to utilize a promising newer mouse model, the D2.B10-Dmdmdx/J (D2/mdx), which has been speculated to recapitulate human pathology better than the commonly used C57BL/10ScSn-Dmdmdx/J (Bl10/mdx).

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