DUCHENNE MUSCULAR DYSTROPHY – CLINICAL

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Cognitive and behavioural abnormalities are a hallmark of dystrophinopathies (DMD/BMD), but little is known about the possible neuroanatomical substrates. To determine the frequency and pattern of intellectual abilities in patients with BMD/DMD, as well as to investigate potential anatomical substrate of these manifestations. 20 patients with DMD/BMD were submitted to the WISC-IV scale. For each subject, volumetric T1 cerebral sequences were obtained in a 3T MRI scanner. A control group of 11 age-matched healthy boys was used for comparison.

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