REGISTRIES AND CARE OF NEUROMUSCULAR DISORDERS

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Quantitative water T1 (T1H2O) mapping has been extensively validated to monitor inflammation, necrosis or fibrosis in myocardial tissues and might represent an efficient alternative to water T2 maps for neuromuscular diseases (NMDs) too. However, in presence of fatty infiltrated skeletal muscles, a “global” T1 value would mainly reflect the intramuscular fat content. To avoid this, we proposed here a novel sequence, inspired by the MR fingerprinting (MRF) method, allowing simultaneous estimation of T1H2O and fat fraction (FF) in the skeletal muscles.

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