Mural cell-derived laminin-α5 plays a detrimental role in ischemic stroke

By Abhijit Nirwane, Jessica Johnson, Benjamin Nguyen, Jeffrey H. Miner and Yao Yao On Feb 18, 2019

At the blood-brain barrier (BBB), laminin-α5 is predominantly synthesized by endothelial cells and mural cells. Endothelial laminin-α5 is dispensable for BBB maintenance under homeostatic conditions but inhibi…