Very long-term outcome in resected and non-resected patients with temporal lobe epilepsy with medial temporal lobe sclerosis: a multiple case-study

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Epilepsy surgery is the most effective treatment option for refractory temporal lobe epilepsy (TLE) with a “good outcome” (i.e., usually seizure- free for at least one year, auras not considered) for about 65% of patients in epilepsy surgery in general [1]. Patients’ decisions in favor of or against surgery are based on a complex trade-off between the chances of seizure-freedom and patients’ subjective expectations [2], on the one hand, and the risks of postoperative cognitive decline [3,4] and further neurological and surgical complications [5], on the other hand.

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