EP.32Quantitative assessment of muscle involvement in limb girdle muscular dystrophy 2Aand 2B


Limb girdle muscular dystrophy (LGMD) 2A and 2B represent the most frequent forms of LGMDs in the Japanese population. We investigated muscle CT images of both LGMDs quantitatively to characterize muscle involvement of this disease and to determine the rate of progression. We have developed new indices, muscle volume index (MVI) and %MVI. MVI is the estimated muscle volume contained within a given CT slice and calculated using the CT histogram-based procedure after correcting for a partial volume effect.


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