Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch


Two related retinal cell types called ON and OFF starburst amacrines migrate to distinct laminae and signal increased (ON) or decreased (OFF) illumination. Fezf1 acts as a fate switch between the two types by activating ON and repressing OFF genes.


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