Basolateral Amygdala Drives a GPCR-Mediated Striatal Memory Necessary for Predictive Learning to Influence Choice

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Predictive learning guides future choices between actions. Here, Morse et al. demonstrate that this fundamental decision-making process is mediated by a novel GPCR-based memory involving the expression of delta-opioid receptors on cholinergic interneurons in the nucleus accumbens shell.

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