Phenytoin versus fosphenytoin for second-line treatment of status epilepticus: propensity score matching analysis using a nationwide inpatient database


Status epilepticus (SE) is an emergency condition in which a rapid seizure cessation and circulation/respiration maintenance are crucially important for avoiding death and irreversible cerebral damage [1,2]. Benzodiazepines have been established as first-line treatment for SE [3,4]. Second-line treatments of longer-acting antiepileptic drugs (AEDs) are administered later to stop SE definitely and prevent recurrence [5].


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