The Association Between HLA-A*03:01 and HLA-B*07:02 Alleles and Oxcarbazepine-induced Maculopapular Eruption in the Uighur Chinese Population


Epilepsy is one of the most common neurological conditions, with more than 2% of the worldwide population affected, according to the latest study [1]. Patients with epilepsy need long-term or lifelong aromatic antiepileptic drugs (AEDs) [2]. Maculopapular eruption (MPE) is the most common clinical manifestation of cutaneous adverse drug reactions (cADRs) in patients taking aromatic AEDs [3]. MPE is characterized by small pink patches and papules on the skin. Clinically, the overall incidence of various forms of AED-induced cADRs is approximately 10% [4].


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