The value of rapid eye movement sleep in the localization of epileptogenic foci for patients with focal epilepsy

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Epilepsy is one of the common neurological diseases, characterized by abnormally synchronized discharges of brain neurons [1]. There are more than 50 million epileptic patients worldwide, 30% of whom are refractory [2], and the poor therapeutic effects contribute heavy psychological and economic burdens on patients and their own families. Epileptic surgery can sometimes have seizure free or reduce the frequency of seizures, of which the premise is to accurately localize the epileptogenic foci. Currently, the localization of epileptogenic foci involves comprehensive preoperative evaluation mainly including semiology, electrophysiology, imaging and nuclear medicine [3].

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