Epilepsy surgery for pediatric patients with mild malformation of cortical development

0

According to Palmini’s classification, the presence of “excess” heterotopic neurons in the molecular layer or white matter is classified as mild malformation of cortical development (mMCD). [1,2] Excess heterotopic neurons in white matter are a frequent pathological finding in many epilepsy surgery specimens, either in isolation or near the epileptogenic lesion [3–5].However, no exact pathomechanistic hypotheses have arisen from this observation, and its role in the causation of epilepsy is debatable [6,7].A few studies correlating mMCD findings with clinical parameters have had small sample sizes and report inconsistent results [8–11].

Read More...

Leave A Reply