Seizures in the neonate: A review of etiologies and outcomes

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Seizures are the most frequent neurological sign observed in the neonatal intensive care unit and occur in their majority in close temporal relation to an acute brain injury or systemic insult, with or without identifiable structural abnormalities [1]. These events are defined as acute symptomatic or provoked seizures. Although these two terms are often used interchangeably, acute symptomatic seizures are in fact defined as resulting from an acute brain injury, such as stroke, trauma or brain infection, whereas provoked seizures are defined as resulting from transient and reversible brain alterations of metabolic or toxic origin [2].

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