Browsing Category

Brain Tumours

Steering CAR T Cells into Solid Tumors

Chimeric antigen receptor (CAR) T cells have been strikingly successful in the treatment of hematologic cancers but have not been effective against solid tumors thus far. A recent report by Samaha and colleagues presents a preclinical…

Neuroblastoma and Histone Demethylation

Neuroblastoma is a childhood cancer of the sympathetic nervous system, with a propensity for widespread metastasis and aggressive clinical behavior. For patients with so-called high-risk disease (typically patients 18 months of age or older…

Exploiting Viruses to Treat Diseases

Viruses have evolved to cause both indolent and explosive disease outbreaks, with millions of people infected with the human immunodeficiency virus and hepatitis viruses and with the current outbreaks of Ebola, yellow fever, and Zika…