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Epilepsy

Assessment of the long‐term efficacy and safety of adjunctive perampanel in tonic‐clonic seizures:…

Abstract Objective This post hoc analysis evaluated long‐term efficacy and safety in patients with focal to bilateral tonic‐clonic seizures (FBTCS) or generalized tonic‐clonic seizures (GTCS) who entered open‐label extension (OLEx) studies…

P‐glycoprotein overactivity in epileptogenic developmental lesions measured in vivo using…

Abstract Objective Overexpression of the drug transporter P‐glycoprotein (P‐gp) is thought to be involved in drug‐resistance in epilepsy by extrusion of antiepileptic drugs (AEDs). We used positron emission tomography (PET) and the P‐gp…