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Epilepsy

High concordance between hippocampal transcriptome of the mouse intra‐amygdala kainic acid model and…

Abstract Objective Pharmacoresistance and the lack of disease‐modifying actions of current antiseizure drugs persist as major challenges in the treatment of epilepsy. Experimental models of chemoconvulsant‐induced status epilepticus remain…

Focal nonmotor versus motor seizures: The impact on diagnostic delay in focal epilepsy

Abstract Objective To test the hypothesis that people with focal epilepsy experience diagnostic delays that may be associated with preventable morbidity, particularly when seizures have only nonmotor symptoms, we compared time to…

Fenfluramine HCl (Fintepla®) provides long‐term clinically meaningful reduction in seizure…

Abstract Objective Fenfluramine has been shown to provide clinically meaningful and statistically significant reductions in convulsive seizure frequency in children and adolescents (aged 2‐18 years) with Dravet syndrome in two randomized,…