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Neuropathology

Activation of Toll-like receptor 5 in microglia modulates their function and triggers neuronal…

Microglia are the primary immune-competent cells of the central nervous system (CNS) and sense both pathogen- and host-derived factors through several receptor systems including the Toll-like receptor (TLR) fa...

Distinct microglial and macrophage distribution patterns in the concentric and lamellar lesions in…

Abstract TMEM119 and purinergic receptor P2Y12 (P2RY12), which are not expressed by recruited peripheral blood macrophages, are proposed to discriminate microglia from macrophages. Therefore, we investigated the distribution patterns of…