Sign in
Sign in
Recover your password.
A password will be e-mailed to you.
Browsing Category
Neuroscience
LRRK2-Related Parkinson’s Disease Due to Altered Endolysosomal Biology With Variable Lewy Body…
Mutations in the gene encoding for leucine-rich repeat kinase 2 (LRRK2) are associated with both familial and sporadic Parkinson’s disease (PD). LRRK2 encodes a large protein comprised of a GTPase and a kinase domain. All pathogenic…
Integrated Automatic Detection, Classification and Imaging of High Frequency Oscillations With…
ObjectiveDuring presurgical evaluation for focal epilepsy patients, the evidence supporting the use of high frequency oscillations (HFOs) for delineating the epileptogenic zone (EZ) increased over the past decade. This study aims to develop…
Machine Learning Representation of Loss of Eye Regularity in a Drosophila Neurodegenerative Model
The fruit fly compound eye is a premier experimental system for modeling human neurodegenerative diseases. The disruption of the retinal geometry has been historically assessed using time-consuming and poorly reliable techniques such as…
Multimodal MRI Longitudinal Assessment of White and Gray Matter in Different SPG Types of Hereditary…
Hereditary spastic paraplegias (HSP) are a group of genetically and clinically heterogeneous neurologic disorders. Hereby we describe a relatively large group of patients (pts) affected by HSP studied at baseline (31 pts) and at follow-up…
Rigbox: An Open-Source Toolbox for Probing Neurons and Behavior
Setting up an experiment in behavioral neuroscience is a complex process that is often managed with ad hoc solutions. To streamline this process we developed Rigbox, a high-performance, open-source software toolbox that facilitates a…
Rigbox: An Open-Source Toolbox for Probing Neurons and Behavior
Setting up an experiment in behavioral neuroscience is a complex process that is often managed with ad hoc solutions. To streamline this process we developed Rigbox, a high-performance, open-source software toolbox that facilitates a…
A HIF1a-dependent pro-oxidant state disrupts synaptic plasticity and impairs spatial memory in…
Sleep apnea causes cognitive deficits and is associated with several neurologic diseases. Intermittent hypoxia (IH) is recognized as a principal mediator of pathophysiology associated with sleep apnea, yet the basis by which IH contributes…
A HIF1a-dependent pro-oxidant state disrupts synaptic plasticity and impairs spatial memory in…
Sleep apnea causes cognitive deficits and is associated with several neurologic diseases. Intermittent hypoxia (IH) is recognized as a principal mediator of pathophysiology associated with sleep apnea, yet the basis by which IH contributes…
Sex differences in biophysical signatures across molecularly defined medial amygdala neuronal…
The medial amygdala (MeA) is essential for processing innate social and non-social behaviors, such as territorial aggression and mating, which display in a sex-specific manner. While sex differences in cell numbers and neuronal morphology…