Sign in
Sign in
Recover your password.
A password will be e-mailed to you.
Browsing Category
Neuroscience
Cortical Inactivation Does Not Block Response Enhancement in the Superior Colliculus
Repetitive visual stimulation is successfully used in a study on the visual evoked potential (VEP) plasticity in the visual system in mammals. Practicing visual tasks or repeated exposure to sensory stimuli can induce neuronal network…
Impact of Brain Surface Boundary Conditions on Electrophysiology and Implications for…
Volume conduction of electrical potentials in the brain is highly influenced by the material properties and geometry of the tissue and recording devices implanted into the tissue. These effects are very large in EEG due to the volume…
The Importance of Anti-correlations in Graph Theory Based Classification of Autism Spectrum Disorder
With the release of the multi-site Autism Brain Imaging Data Exchange, many researchers have applied machine learning methods to distinguish between healthy subjects and autistic individuals by using features extracted from resting state…
Theta-gamma cross-frequency transcranial alternating current stimulation over the trough impairs…
Cognitive control is a mental process, which underlies adaptive goal-directed decisions. Previous studies have linked cognitive control to electrophysiological fluctuations in the theta band and theta-gamma cross-frequency coupling (CFC)…
New Optical Tools to Study Neural Circuit Assembly in the Retina
During development, neurons navigate a tangled thicket of thousands of axons and dendrites to synapse with just a few specific targets. This phenomenon termed wiring specificity, is critical to the assembly of neural circuits and the way…
Molecular Crosstalk Between Circadian Rhythmicity and the Development of Neurodegenerative Disorders
Neurodegenerative disorders have been shown to exhibit substantial interconnectedness with circadian rhythmicity. Alzheimer’s patients exhibit high degradation of the suprachiasmatic nucleus (SCN), the central endogenous circadian…
Pharmacodynamic Biomarkers for Emerging LRRK2 Therapeutics
Genetic studies have identified variants in the LRRK2 gene as important components of Parkinson’s disease (PD) pathobiology. Biochemical and emergent biomarker studies have coalesced around LRRK2 hyperactivation in disease. Therapeutics…
Sleep Disturbances and Sleep Disordered Breathing Impair Cognitive Performance in Parkinson’s…
BackgroundSleep disturbances and impairment of cognitive function are among the most frequent non-motor symptoms in Parkinson’s disease (PD) with negative implications on quality of life of patients and caregivers. Despite the fact that…
Blood-Brain Barrier: More Contributor to Disruption of Central Nervous System Homeostasis Than…
The blood-brain barrier (BBB) is a dynamic but solid shield in the cerebral microvascular system. It plays a pivotal role in maintaining central nervous system (CNS) homeostasis by regulating the exchange of materials between the…
Bergapten Improves Scopolamine-Induced Memory Impairment in Mice via Cholinergic and Antioxidative…
Bergapten is a furanocoumarin naturally occurring in the Apiaceae family and it is a well-known photosensitizing agent used in photochemotherapy. In this study, we investigated the influence of bergapten on cognitive function and mechanism…