Browsing Tag

epilepsy treatment

Epilepsy syndromes, etiologies, and the use of next‐generation sequencing in epilepsy presenting in…

Abstract Objective Population‐based data on epilepsy syndromes and etiologies in early onset epilepsy are scarce. The use of next‐generation sequencing (NGS) has hitherto not been reported in this context. The aim of this study is to…

Characterization of kindled VGAT‐Cre mice as a new animal model of temporal lobe epilepsy

Abstract Objective Development of novel therapies for temporal lobe epilepsy is hindered by a lack of models suitable for drug screening. While testing the hypothesis that “inhibiting inhibitory neurons” was sufficient to induce seizures,…

Value of 7T MRI and post‐processing in patients with nonlesional 3T MRI undergoing epilepsy…

Abstract Objective Ultra‐high‐field 7‐Tesla (7T) magnetic resonance imaging (MRI) offers increased signal‐to‐noise and contrast‐to‐noise ratios, which may improve visualization of cortical malformations. We aim to assess the clinical value…

Seizures with paroxysmal arousals in sleep‐related hypermotor epilepsy (SHE): Dissecting epilepsy…

Abstract Objective Sleep‐related hypermotor epilepsy (SHE) is a focal epilepsy characterized by seizures occurring mostly during sleep, ranging from brief seizures with paroxysmal arousals (SPAs) to hyperkinetic seizures and ambulatory…

Interrater agreement on classification of photoparoxysmal electroencephalographic response

Abstract Our goal was to assess the interrater agreement (IRA) of photoparoxysmal response (PPR) using the classification proposed by a task force of the International League Against Epilepsy (ILAE), and a simplified classification system…