Browsing Tag

neurology

Causal associations between modifiable risk factors and the Alzheimer’s phenome

Objective To infer causal relationships between 22 previously reported risk factors for Alzheimer’s disease (AD) and the “AD phenome”: AD, AD age of onset (AAOS), hippocampal volume, cortical surface area and thickness, cerebrospinal fluid…

A stearoyl‐CoA desaturase inhibitor prevents multiple Parkinson’s disease‐phenotypes in…

Objective Parkinson's disease (PD) has useful symptomatic treatments that do not slow the neurodegenerative process, and no significant disease‐modifying treatments are approved. A key therapeutic target in PD is α‐synuclein (αS), which is…

Prior anticoagulation in patients with ischaemic stroke and atrial fibrillation

Objective To evaluate in patients with atrial fibrillation (AF) and acute ischaemic stroke the association of prior anticoagulation with vitamin‐K antagonists (VKA) or direct oral anticoagulants (DOACs) with stroke severity, intravenous…