Browsing Tag

neuron

The Parabrachial Nucleus Directly Channels Spinal Nociceptive Signals to the Intralaminar Thalamic…

Deng et al. demonstrate that the ipsilateral spinoparabrachial pathway mediates nocifensive behavior and identify that the Tacr1+ neurons in the parabrachial nucleus represent the major target of the spinal projection. The authors also…

COVID-19 and the chemical senses: supporting players take center stage

The main neurological manifestation of COVID-19 is loss of smell or taste. The high incidence of smell loss without significant rhinorrhea or nasal congestion suggests that SARS-CoV-2 targets the chemical senses through mechanisms distinct…

VTA Glutamate Neuron Activity Drives Positive Reinforcement Absent Dopamine Co-release

Activation of VTA glutamate neurons leads to dopamine co-release in nucleus accumbens. Zell et al. genetically block this dopamine signal to show that VTA glutamate projections to nucleus accumbens can reinforce behaviors independently.…