Browsing Tag

neuropathology

Associations of mitochondrial genomic variation with corticobasal degeneration, progressive…

Mitochondrial health is important in ageing and dysfunctional oxidative phosphorylation (OXPHOS) accelerates ageing and influences neurodegeneration. Mitochondrial DNA (mtDNA) codes for vital OXPHOS subunits a...

Aggregate-selective antibody attenuates seeded aggregation but not spontaneously evolving disease in…

Increasing evidence suggests that propagation of the motor neuron disease amyotrophic lateral sclerosis (ALS) involves the pathogenic aggregation of disease-associated proteins that spread in a prion-like mann...