Brain Tumours

admin September 12, 2019

To the Editor: Pennsylvania legalized medical marijuana in 2016, and since then its use has skyrocketed. The doses of the active ingredients of marijuana — tetrahydrocannabinol (THC) and cannabidiol (CBD) — are not standardized, product concentrations are not regulated, and prescribing practices…

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admin August 8, 2019

You can’t walk into a pediatric intensive care unit (PICU) anywhere in the world without being viscerally struck by sights, smells, and sounds that can easily overwhelm the uninitiated. Every child in a PICU is attached to various monitors that seem to reduce that child’s life to a set of vital…

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admin February 1, 2019

Chimeric antigen receptor (CAR) T cells have been strikingly successful in the treatment of hematologic cancers but have not been effective against solid tumors thus far. A recent report by Samaha and colleagues presents a preclinical version of CAR T-cell therapy for a solid tumor, glioblastoma.…

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admin October 12, 2018

Neuroblastoma is a childhood cancer of the sympathetic nervous system, with a propensity for widespread metastasis and aggressive clinical behavior. For patients with so-called high-risk disease (typically patients 18 months of age or older who present with metastatic disease), standard therapy is…

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admin September 1, 2018

Most practicing physicians will recall from their training that the average prognosis for patients with central nervous system (CNS) metastases from melanoma was death within a matter of weeks to months. This reflected the natural history of a disease on which systemic treatment had a negligible…

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