Epilepsy

Delphine Taussig November 17, 2018

Epilepsy surgery was first described by Horsley [1]. In Montreal in 1937, Penfield and Jasper began performing acute intraoperative electrocorticography in awake patients combined with electrical stimulations in the same step as the surgical treatment [2]. The tailored resection relied on interictal epileptiform abnormalities and on the rare recorded seizures.… Read More...

Jonathan Dallas, Dario J. Englot, Robert P. Naftel November 17, 2018

Epilepsy is one of the most common neurological conditions seen in pediatric patients. While a majority of cases are effectively treated with anti-epileptic medications (AEDs), roughly one-third of patients will remain refractory to medical treatment[1–3]. Failure to appropriately address seizures in children can result in further negative outcomes, including bodily injury and negative psychosocial sequalae[2].… Read More...

Stanislas Lagarde, Sinziana Buzori, Agnès Trebuchon, Romain Carron, Didier Scavarda, Mathieu Milh, Aileen McGonigal, Fabrice Bartolomei November 16, 2018

Summary

Objective

In this study, we seek to analyze the determinants of the intracranial electroencephalography seizure onset pattern (SOP) and the impact of the SOP in predicting postsurgical seizure outcome.

Methods

To this end, we analyzed 820 seizures from 252 consecutive patients explored by stereo‐electroencephalography (total of 2148 electrodes), including various forms of focal refractory epilepsies.… Read More...

Nicholas H. Couturier, Dominique M. Durand November 16, 2018

Summary

Objective

Low‐frequency fiber‐tract stimulation has been shown to be effective in treating mesial temporal lobe epilepsies through activation of the hippocampal commissure in rodents and human patients. The corpus callosum is a major pathway connecting the two hemispheres of the brain; however, few experiments have documented corpus callosum stimulation.… Read More...

Emmely Rodin, Martin H. Krogstad, Preben Aukland, Martin Lando, Harald S. Møller, Joanna Gesche, Thomas Krøigård, Christoph P. Beier November 16, 2018

Summary

Objective

To determine annual incidence, etiology, severity, and short‐ and long‐term mortality of first‐time, nonanoxic status epilepticus (SE) in adults in a population‐based retrospective cohort study.

Methods

We systematically identified all episodes of SE in the year 2014 on the island of Funen.… Read More...

José L. Fernández-Torre, Alicia Paramio-Paz, Icíar Lorda de los Ríos, María Martín-García, Miguel A. Hernández-Hernández November 16, 2018

Pupillary hippus (PH) refers to spontaneous bilateral synchronous rhythmic constriction and dilatation of the pupils [1]. This rare phenomenon is spasmodic, cyclic and bilaterally in phase, and is usually considered benign [2]. However, this clinical sign can rarely be the main manifestation of refractory epilepsy and nonconvulsive status epilepticus (NCSE) in critically ill patients [1,3–4].… Read More...

Geraldine Lines, William Henley, Robert Winterhalder, Rohit Shankar November 14, 2018

Comorbid epilepsy is found in 22.5% of people with ID, a prevalence positively correlated with severity of ID [1,2]. The link between behavioural disturbance in people with ID and epilepsy is complex and poorly understood [3,4]. There is a paucity of research [5,6].… Read More...

Linda Kalilani, Xuezheng Sun, Barbara Pelgrims, Matthias Noack‐Rink, Vicente Villanueva November 14, 2018

Summary

Objective

The definition of drug‐resistant epilepsy (DRE) affects case identification and treatment, and impacts prevalence or incidence estimates and health burden estimation in epidemiology. The objective of this systematic review is to evaluate the consistency between definitions of DRE in the literature and the official definition in the International League Against Epilepsy (ILAE) guidelines, and to estimate the incidence, prevalence, and risk factors for DRE.… Read More...

Robert Colebunders, Jane Y Carter, Peter Claver Olore, Kai Puok, Samit Bhattacharyya, Sonia Menon, Gasim Abd-Elfarag, Morrish Ojok, Chellafe Ensoy-Musoro, Richard Lako, Makoy Yibi Logora November 13, 2018

South Sudan is amongst the highly endemic countries for onchocerciasis in Africa, with the disease endemic in around half (49%) the country (1). The most highly endemic foci of onchocerciasis in South Sudan are in Western Equatoria, and Northern and Western Bahr el Ghazal regions.… Read More...

Tomokazu Kimizu, Yukitoshi Takahashi, Taikan Oboshi, Asako Horino, Hirowo Omatsu, Takayoshi Koike, Shinsaku Yoshitomi, Tokito Yamaguchi, Hideyuki Otani, Hiroko Ikeda, Katsumi Imai, Hideo Shigematsu, Yushi Inoue November 13, 2018

The reported risk of developing post-encephalitic/encephalopathic epilepsy (PEE) in patients who had acute encephalitis/encephalopathy was 6.8% and 16.4% [1,2]. Previous studies have shown that PEE accounts for 5.5% and 10.4% of patients with intractable epilepsy [3,4]. PEE is recognized as drug-resistant epilepsy, and patients with PEE are often affected by adverse effects related to poly-pharmaceutical therapy.… Read More...

Andoird App
Loading...