Epilepsy

Rianne J. M. Goselink, Jeroen J. van Dillen, Marjolein Aerts, Johan Arends, Charlotte van Asch, Inge van der Linden, Jaco Pasman, Christiaan G. J. Saris, Machiel Zwarts, Nens Alfen July 18, 2019

Abstract

To improve the diagnostic accuracy of electroencephalography (EEG) criteria for nonconvulsive status epilepticus (NCSE), external validation of the recently proposed Salzburg criteria is paramount. We performed an external, retrospective, diagnostic accuracy study of the Salzburg criteria, using EEG recordings from patients with and without a clinical suspicion of having NCSE.… Read More...

Zhaoshi Yi, Huaping Wu, Xiongying Yu, Jian Zha, Hui Chen, Yong Chen, Jianmin Zhong July 17, 2019

Infantile spasms (IS) has been described as a challenging epilepsy syndrome because its drug resistance and poor prognosis, which have given rise to a large burden on society and patients’ families. IS typically have an onset between 3 and 12 months of age with a peak incidence around 6-7 months [1].However, the patients were divided into three groups by age at onset of spasms [2]: early onset ( less than 3 months), classic onset (3 months and up to 12 months), and late onset (12 months and older), respectively.… Read More...

Euloge Ibinga, Michel Druet-Cabanac, Marc Harris Dassi Tchoupa Revegue, Jean Engohang-Ndong, Ulrick Bisvigou, Simon Jonas Ategbo, Pierre-Marie Preux, Edgard Brice Ngoungou July 17, 2019

Epilepsy is a common disorder that occurs worldwide in all age groups and without distinction of gender. There are many superstitious beliefs in African counties about etiology of epilepsy [1–5]. In some of these countries, traditional healers, teachers, and students have linked epilepsy to spiritual attacks and witchcraft.… Read More...

Scott T. Demarest, Heather E. Olson, Angela Moss, Elia Pestana‐Knight, Xiaoming Zhang, Sumit Parikh, Lindsay C. Swanson, Katherine D. Riley, Grace A. Bazin, Katie Angione, Lisa‐Marie Niestroj, Dennis Lal, Elizabeth Juarez‐Colunga, Tim A. Benke July 17, 2019

Abstract

Objective

The cyclin‐dependent kinase like 5 (CDKL5) gene is a known cause of early onset developmental and epileptic encephalopathy, also known as CDKL5 deficiency disorder (CDD). We sought to (1) provide a description of seizure types in patients with CDD, (2) provide an assessment of the frequency of seizure‐free periods and cortical visual impairment (CVI), (3) correlate these features with genotype and gender, and (4) correlate these features with developmental milestones.… Read More...

Priyanka Madaan, Prashant Jauhari, Biswaroop Chakrabarty, Sheffali Gulati July 16, 2019

Glucose transporter-1 (GLUT1)/SLC2A1 is expressed at the highest levels in brain capillaries, astroglia, and erythrocytes. GLUT1-deficiency syndrome is a neurological disorder resulting primarily from aberrant glucose transport into the brain. Clinically, it is classified as GLUT1-deficiency syndrome with epilepsy and without epilepsy.… Read More...

Erik Kaestner, Anny Reyes, Anna Christina Macari, Yu‐Hsuan Chang, Brianna M. Paul, Bruce P. Hermann, Carrie R. McDonald July 13, 2019

Abstract

Objective

To identify neuroimaging and clinical biomarkers associated with a language‐impaired phenotype in refractory temporal lobe epilepsy (TLE).

Methods

Eighty‐five patients with TLE were characterized as language‐impaired (TLE‐LI) or non–language‐impaired (TLE‐NLI) based on comprehensive neuropsychological testing. Structural magnetic resonance imaging (MRI), diffusion tensor imaging, and functional MRI (fMRI) were obtained in patients and 47 healthy controls (HC).… Read More...

Norman Delanty, Maire White, Katherine Benson, Mark McCormack, Sinead Heavin, Elizabeth Comerford, Nisha Gangadharan, Kevin Power, Brendan Dunleavey, Hany El‐Naggar, Colin Doherty, Marie Greally, Gianpiero Cavalleri, Mary Fitzsimons July 12, 2019

Abstract

Objectives

Both clinical genomics and e‐Health technology are changing the way medicine is being practiced. Although the basic clinical methodology of good medical care will remain unchanged, the combined power of genomics and electronic health records has the capability of enhancing, and in some cases transforming, the practice of medicine.… Read More...

Yiwei Zhang, Yuelei Lv, Hui You, Wanchen Dou, Bo Hou, Lin Shi, Zhentao Zuo, Weiyu Mao, Feng Feng July 10, 2019

Magnetic resonance imaging (MRI) is a well-recognized diagnostic tool in most brain disorders. Today, high-strength magnetic field (3 Tesla) MRI are standard. Though 7 T MRI are not currently widely used yet, it becomes more and more available for clinical and neuroscientific researchers.… Read More...

Andoird App
Loading...